Scer\GAL4Ilp3.PB, hidUAS.cHa, rprUAS.C has neurosecretory neuron phenotype
Co-expression of WScer\UAS.cHa and rprScer\UAS.C under the control of Scer\GAL4Ilp3.PB ablates all of the insulin-producing cells (IPCs) specifically at the postlarval stage (larval IPCs are not ablated).
Flies co-expressing WScer\UAS.cHa and rprScer\UAS.C under the control of Scer\GAL4Ilp3.PB and raised on fly maintenance food show no change in longevity compared to wild-type controls. Flies co-expressing WScer\UAS.cHa and rprScer\UAS.C under the control of Scer\GAL4Ilp3.PB and raised on fly food with yeast paste show an increase in life span compared to wild-type controls.