FlyBase Allele Report: Dmel\Tlk[UAS.Tag:FLAG]

General Information

Symbol

Dmel\Tlk^UAS.Tag:FLAG

Species

D. melanogaster

Name

FlyBase ID

FBal0241977

Feature type

allele

Associated gene

Dmel\Tlk

Associated Insertion(s)

Carried in Construct

P{UAS-Tlk.FLAG}

Also Known As

UAS-Tlk

Key Links

Transgenic product class

wild_type

(Merdes, 2010.2.24)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Merdes, 2010.2.24)

Mutagen

in vitro construct

(Merdes, 2010.2.24)

Progenitor genotype

Carried in construct

P{UAS-Tlk.FLAG}

Cytology

Description

UAS sequences drive expression of Tlk tagged at the C-terminus with Tag:FLAG.

(Merdes, 2010.2.24)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tlk

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

short lived, with Scer\GAL4^da.Switch.PT

(Gong and Cheng, 2026)

short lived, with Scer\GAL4^Mhc.F3-580

(Gong and Cheng, 2026)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^da.Switch.PT, Tlk^UAS.Tag:FLAG has short lived phenotype, enhanceable by Hsap\SNCA^UAS.cJa, Scer\GAL4^da.Switch.PT

(Gong and Cheng, 2026)

Scer\GAL4^Mhc.F3-580, Tlk^UAS.Tag:FLAG has short lived phenotype, enhanceable by Hsap\ASIC2^G430C.UAS, Scer\GAL4^Mhc.F3-580

(Gong and Cheng, 2026)

Enhancer of

Statement

Reference

Tlk^UAS.Tag:FLAG, Scer\GAL4^da.Switch.PT is an enhancer of short lived phenotype of Hsap\SNCA^UAS.cJa, Scer\GAL4^da.Switch.PT

(Gong and Cheng, 2026)

Tlk^UAS.Tag:FLAG, Scer\GAL4^Mhc.F3-580 is an enhancer of short lived phenotype of Hsap\ASIC2^G430C.UAS, Scer\GAL4^Mhc.F3-580

(Gong and Cheng, 2026)

Phenotype Manifest In

Enhancer of

Statement

Reference

Tlk^UAS.Tag:FLAG, Scer\GAL4^da.Switch.PT is an enhancer of mitochondrion | adult stage phenotype of Hsap\SNCA^UAS.cJa, Scer\GAL4^da.Switch.PT

(Gong and Cheng, 2026)

Tlk^UAS.Tag:FLAG, Scer\GAL4^da.Switch.PT is an enhancer of adult brain phenotype of Hsap\SNCA^UAS.cJa, Scer\GAL4^da.Switch.PT

(Gong and Cheng, 2026)

Tlk^UAS.Tag:FLAG, Scer\GAL4^Mhc.F3-580 is an enhancer of mitochondrion | adult stage phenotype of Hsap\ASIC2^G430C.UAS, Scer\GAL4^Mhc.F3-580

(Gong and Cheng, 2026)

Tlk^UAS.Tag:FLAG, Scer\GAL4^Mhc.F3-580 is an enhancer of indirect flight muscle | adult stage phenotype of Hsap\ASIC2^G430C.UAS, Scer\GAL4^Mhc.F3-580

(Gong and Cheng, 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

29963

w¹¹¹⁸; P{UAS-Tlk.FLAG}2

29964

w¹¹¹⁸; P{UAS-Tlk.FLAG}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Tlk^{Scer\UAS.T:Zzzz\FLAG}

Tlk^UAS.Tag:FLAG

tlk^{Scer\UAS.T:Zzzz\FLAG}

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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