FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AcslUAS.715.C.Tag:MYC
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General Information
Symbol
Dmel\AcslUAS.715.C.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0242928
Feature type
allele
Associated gene
Dmel\Acsl
Associated Insertion(s)
Carried in Construct
P{UAS-Acsl.715.MycC}
Also Known As
UAS-Acsl::myc, UAS-Acsl-Myc
Key Links
Transgenic product class
wild_type
(Zhang et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zhang et al., 2009)
Mutagen
in vitro construct
(Zhang et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Acsl.715.MycC}
Cytology
Description

UAS sequences drive expression of the 715 amino acid Acsl isoform plus a C-terminal 6x Tag:MYC tag.

(Zhang et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Acsl
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  non-syndromic X-linked intellectual disability
      modeled by Acsl05847, Acsl8
      (Jia et al., 2019)
      modeled by AcslKO
      (Jia et al., 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Neutral lipid accumulation is increased in the posterior compartment of Scer\GAL4en-e16E, AcslScer\UAS.715.T:Hsap\MYC.C wings discs.

      (Zhang et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/AcslUAS.715.C.Tag:MYC rescues Acsl05847/AcslKO

      (Liu et al., 2014)

      AcslUAS.715.C.Tag:MYC/Scer\GAL4Tub.PU rescues Acsl8/Acslk10313

      (Zhang et al., 2009)

      AcslUAS.715.C.Tag:MYC/Scer\GAL4Tub.PU rescues Acsl05847/Acsl8

      (Zhang et al., 2009)
      Partially rescues

      AcslUAS.715.C.Tag:MYC/Scer\GAL4Tub.PU partially rescues Acsl1/Acsl8

      (Zhang et al., 2009)

      AcslUAS.715.C.Tag:MYC/Scer\GAL4Tub.PU partially rescues Acsl05847/Acsl8

      (Zhang et al., 2009)
      Fails to rescue

      AcslUAS.715.C.Tag:MYC/Scer\GAL4dpp.blk1 fails to rescue Acsl8/Acslk10313

      (Zhang et al., 2009)
      Comments

      Scer\GAL4elav-C155-mediated expression of AcslScer\UAS.715.C.T:Hsap\MYC rescues the increased total and satellite bouton number in neuromuscular junction 4 of the anterior segments A2 and A3 in Acsl05847/AcslKO animals.

      (Liu et al., 2014)

      Expression of AcslScer\UAS.715.T:Hsap\MYC.C under the control of Scer\GAL4tub partially rescues the lethality associated with the Acsl8/Acsl1 and Acsl8/Acsl05847 genotypes.

      Expression of AcslScer\UAS.715.T:Hsap\MYC.C under the control of Scer\GAL4tub restores neutral lipid staining in Acsl8/Acsl05847 wing discs.

      Expression of AcslScer\UAS.715.T:Hsap\MYC.C under the control of Scer\GAL4tub restores well-ordered axon projection in the optic lamina of the third instar larval brain of Acsl8/Acslk10313 mutants.

      Expression of AcslScer\UAS.715.T:Hsap\MYC.C under the control of Scer\GAL4dpp.blk1 fails to restore well-ordered axon projection in the optic lamina of the third instar larval brain of Acsl8/Acslk10313 mutants.

      (Zhang et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      AcslScer\UAS.715.C.T:Hsap\MYC
      AcslScer\UAS.715.T:Hsap\MYC.C
      AcslUAS.715.C.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (8)