FlyBase Allele Report: Dmel\mir-ban[20]

General Information

Symbol

Dmel\mir-ban²⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0243240

Feature type

allele

Associated gene

Dmel\mir-ban

Associated Insertion(s)

Carried in Construct

Also Known As

ban²⁰

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Yang et al., 2009)

Mutagen

Delta2-3 transposase

(Yang et al., 2009)

Progenitor genotype

mir-ban^EP3622

(Yang et al., 2009)

Cytology

Description

Has an approximately 21kb deletion (-24.2kb to -2.7kb) upstream of the ban gene.

(Yang et al., 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3L:618,105..639,562 [+]

Comment:

~21kb deletion resulting from the imprecise excision of the P{EP}ban[EP3622] insertion(s). The deletion coordinates were reported as 618105-639562.

(Yang et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

sterile

(Yang et al., 2009)

sterile (with Df(3L)emc-E12)

(Yang et al., 2009)

viable

(Yang et al., 2009)

viable (with Df(3L)emc-E12)

(Yang et al., 2009)

Phenotype Manifest In

germline stem cell (with Df(3L)emc-E12)

(Yang et al., 2009)

Detailed Description

Statement

Reference

Heterozygous ban²⁰ has no effect on eye morphology.

(Tan et al., 2012)

Two day old germaria from ban²⁰/Df(3L)emc-E12 animals contain an average of 1.54 germline stem cells, which is fewer than controls (2-3 per germarium). This drops to 0.80 in 7 day old mutant germaria, and 0.33 in 14 day old mutant germaria, compared to controls which maintain approximately 2 germline stem cells.

(Yang et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

ban[+]/mir-ban²⁰ is a non-enhancer of visible | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

ban[+]/mir-ban²⁰ is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Suppressor of

Statement

Reference

mir-ban²⁰/mir-ban²⁰ is a suppressor | partially of increased cell number | germline clone | oogenesis phenotype of bgcn^MI06696/bgcn¹

(Zhang et al., 2024)

Other

Statement

Reference

bgcn^MI06696/bgcn¹, mir-ban²⁰/mir-ban¹² has decreased cell number | oogenesis phenotype

(Zhang et al., 2024)

bgcn^MI06696/bgcn¹, mir-ban²⁰/mir-ban¹² has cell lethal | germline clone | oogenesis phenotype

(Zhang et al., 2024)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

ban[+]/mir-ban²⁰ is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

ban[+]/mir-ban²⁰ is a non-enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, Zzzz\CGG^90.UAS.EGFP

(Tan et al., 2012)

Suppressor of

Statement

Reference

mir-ban²⁰/mir-ban²⁰ is a suppressor | partially of female germline cell | increased number | germline clone phenotype of bgcn^MI06696/bgcn¹

(Zhang et al., 2024)

Other

Statement

Reference

bgcn^MI06696/bgcn¹, mir-ban²⁰/mir-ban¹² has female germline cell | absent phenotype

(Zhang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

One copy of ban²⁰ has no effect on the fused ommatidia phenotype seen when Avic\GFP^{Fmr1.CGG90.E.Scer\UAS} is expressed under the control of Scer\GAL4^GMR.PF.

(Tan et al., 2012)

Complementation and Rescue Data

Rescued by

mir-ban²⁰/Df(3L)emc-E12 is rescued by mir-ban^+t7.2

(Yang et al., 2009)

Comments

The sterile and reduced germline stem cell phenotype of ban²⁰/Df(3L)emc-E12 is rescued with the introduction of ban^+t7.2.

(Yang et al., 2009)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ban²⁰

(Zhang et al., 2024, Tan et al., 2012, Yang et al., 2009)

mir-ban²⁰

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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