FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lnk+t6
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General Information
Symbol
Dmel\Lnk+t6
Species
D. melanogaster
Name
FlyBase ID
FBal0243730
Feature type
allele
Associated gene
Dmel\Lnk
Associated Insertion(s)
Carried in Construct
P{Lnk.6}
Key Links
Transgenic product class
genomic_DNA
(Werz et al., 2009)
wild_type
(Werz et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Werz et al., 2009)
wild_type
(Werz et al., 2009)
Mutagen
in vitro construct
(Werz et al., 2009)
Progenitor genotype
Carried in construct
P{Lnk.6}
Cytology
Description

6kb genomic fragment containing Lnk.

(Werz et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
Lnk
Encoded product / tool
Lnk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Lnk+t6 rescues LnkDel29

      (Slack et al., 2010)

      Lnk+t6 rescues Lnk6S2/Lnk4Q3

      (Werz et al., 2009)
      Comments

      The reduction in wing area an in body mass which is seen in LnkDel29 flies is fully rescued by Lnk+t6. The increased lifespan seen in homozygous LnkDel29 females is restored to normal by Lnk+t6. Lnk+t6 restores the number of eggs laid by homozygous LnkDel29 females to wild-type levels. Lnk+t6 restores the increased resistance of homozygous LnkDel29 flies to 5% hydrogen peroxide and to starvation to wild-type levels. Lnk+t6 restores the increased levels of whole body triglyceride, glycogen and trehalose that are seen in LnkDel29 flies to wild-type levels.

      (Slack et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lnk+t6
      LnkGR
      (Slack et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)