FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ilp71
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General Information
Symbol
Dmel\Ilp71
Species
D. melanogaster
Name
FlyBase ID
FBal0243899
Feature type
allele
Associated gene
Dmel\Ilp7
Associated Insertion(s)
TI{TI}Ilp71
Carried in Construct
Also Known As
ilp7ko
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
I-SceI
(Grönke et al., 2010)
FLPase
(Grönke et al., 2010)
ends-out gene targeting
(Grönke et al., 2010)
Progenitor genotype
Associated Insertion(s)
TI{TI}Ilp71
Cytology
Description

The entire Ilp7 coding sequence has been replaced by a w+mW.hs marker.

(Grönke et al., 2010)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ilp71mutants show increased mortality as a result of WNV-Kun infection when compared to controls.

      (Ahlers et al., 2019)

      Ilp71 mutant larvae have significantly increased nociceptive movement responses following stimulation with a von Frey filament, compared to controls.

      (Hu et al., 2017)

      Ilp71 mutants are 100% viable; show no delay in egg-to-adult development time; show no reduction in adult body weight; and have normal median lifespan, lifetime fecundity, paraquat resistance, starvation resistance, and lipid and glycogen storage.

      (Grönke et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      Ilp71 is a non-enhancer of viable | female phenotype of Df(3L)Ilp2-3, Ilp51

      (Grönke et al., 2010)

      Ilp71 is a non-enhancer of partially lethal - majority live | male phenotype of Df(3L)Ilp2-3, Ilp51

      (Grönke et al., 2010)

      Ilp71 is a non-enhancer of abnormal developmental rate phenotype of Df(3L)Ilp2-3, Ilp51

      (Grönke et al., 2010)

      Ilp71 is a non-enhancer of decreased fecundity phenotype of Df(3L)Ilp2-3, Ilp51

      (Grönke et al., 2010)

      Ilp71 is a non-enhancer of partially lethal - majority live phenotype of Df(3L)Ilp1-4, Ilp51

      (Grönke et al., 2010)

      Ilp71 is a non-enhancer of abnormal developmental rate phenotype of Df(3L)Ilp1-4, Ilp51

      (Grönke et al., 2010)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of Ilp71 into the Df(3L)Ilp2-3, Ilp51 or Df(3L)Ilp1-4, Ilp51 backgrounds does not further negatively affect the viability, egg-to-adult development time, and adult body weight phenotypes seen in these starting genotypes.

      (Grönke et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Ilp71
      (Fernandes et al., 2017)
      Ilp7ko
      (Imambocus et al., 2022)
      Ilp7[1]
      (Cong et al., 2015)
      ilp71
      (Ahlers et al., 2019)
      ilp7ko
      (Hu et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (8)