FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fryUAS.Tag:MYC.GFP
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General Information
Symbol
Dmel\fryUAS.Tag:MYC.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0244511
Feature type
allele
Associated gene
Dmel\fry
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-fry-GFP}
Also Known As
UAS-myc-fry-GFP
Key Links
Transgenic product class
wild_type
(Fang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Fang et al., 2010)
Mutagen
in vitro construct
(Fang et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Myc-fry-GFP}
Cytology
Description

UAS regulatory sequences drive expression of a fry mini-gene tagged at the 5' end by 6 copies of Tag:MYC and at the 3' end with GFP.

(Fang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fry
Tagged with
GFP
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of fryUAS.Tag:MYC.GFP under the control of Scer\GAL4Act.PU completely rescues the lethality of fry1/fry2 mutants. These rescued flies are both male and female sterile. The paired ovaries of rescued females are often of different sizes, and the eggs produced are more rounded than normal and are rarely laid. Wing cells in adult wings from these rescued flies display (in 99% of cases) a single hair compared to the more than four hairs per cell seen in fry loss of function clones.

      (Fang et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Act.PU/fryUAS.Tag:MYC.GFP partially rescues fry2/fry1

      (Fang et al., 2010)
      Comments

      Expression of fryUAS.Tag:MYC.GFP under the control of Scer\GAL4Act.PU completely rescues the lethality of fry1/fry2 mutants. These rescued flies are both male and female sterile. The paired ovaries of rescued females are often of different sizes, and the eggs produced are more rounded than normal and are rarely laid. Wing cells in adult wings from these rescued flies display (in 99% of cases) a single hair compared to the more than four hairs per cell seen in fry loss of function clones.

      (Fang et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fryScer\UAS.T:Hsap\MYC.T:Avic\GFP
      fryUAS.Tag:MYC.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)