FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tumUAS.Z.Tag:MYC
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General Information
Symbol
Dmel\tumUAS.Z.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0244519
Feature type
allele
Associated gene
Dmel\tum
Associated Insertion(s)
Carried in Construct
P{UAS-tum.MYC.Z}
Key Links
Transgenic product class
cDNA
(Zavortink et al., 2005)
wild_type
(Zavortink et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Zavortink et al., 2005)
wild_type
(Zavortink et al., 2005)
Mutagen
in vitro construct
(Zavortink et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-tum.MYC.Z}
Cytology
Description

UASt regulatory sequences drive expression of a full-length tum cDNA tagged with a C-terminal Tag:MYC fusion.

(Zavortink et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tum
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of tumScer\UAS.Z.T:Hsap\MYC under the control of Scer\GAL4G14 does not result in an abnormal muscle phenotype.

      (Guerin and Kramer, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4G14/tumUAS.Z.Tag:MYC partially rescues tumDH15

      (Guerin and Kramer, 2009)
      Fails to rescue

      tumUAS.Z.Tag:MYC/Scer\GAL469B fails to rescue tumDH15

      (Guerin and Kramer, 2009)
      Comments

      Expression of tumScer\UAS.Z.T:Hsap\MYC under the control of Scer\GAL4prd.RG1 rescues the epidermal cytokinesis defects of tumDH15 embryos, but does not rescue the muscle patterning defects.

      Expression of tumScer\UAS.Z.T:Hsap\MYC under the control of Scer\GAL469B fails to rescue the muscle patterning defects of tumDH15 embryos.

      Expression of tumScer\UAS.Z.T:Hsap\MYC under the control of Scer\GAL4G14 significantly improves muscle morphology and patterning defects in tumDH15 embryos.

      (Guerin and Kramer, 2009)

      Expression of tumScer\UAS.T:Hsap\MYC.cZa in tumDH15 mutant embryos driven by Scer\GAL4prd.RG1 rescues the binucleate phenotype. Stripes of binucleate cells alternate with rescued mononucleate cells.

      (Zavortink et al., 2005)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      tumScer\UAS.T:Hsap\MYC.cZa
      tumScer\UAS.Z.T:Hsap\MYC
      tumUAS.Z.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (3)