FB2026_03 , released September 17, 2026
Allele: Hsap\NRF1elav.PH
Open Close
General Information
Symbol
Hsap\NRF1elav.PH
Species
H. sapiens
Name
embryonic lethal abnormal vision promoter construct of Haussmann
FlyBase ID
FBal0244704
Feature type
allele
Associated gene
Hsap\NRF1
Associated Insertion(s)
Carried in Construct
P{elav-NRF-1.H}
Key Links
Transgenic product class
wild_type
(Haussmann et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Haussmann et al., 2008)
Mutagen
in vitro construct
(Haussmann et al., 2008)
Progenitor genotype
Carried in construct
P{elav-NRF-1.H}
Cytology
Description

elav promoter sequences drive expression of the Hsap\NRF1 open reading frame and ewg 3'UTR sequences.

(Haussmann et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
elav
Encoded product / tool
Hsap\NRF1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hsap\NRF1elav.PH is a suppressor of abnormal neuroanatomy | larval stage phenotype of ewg2

      (Haussmann et al., 2008)

      Hsap\NRF1elav.PH is a suppressor of lethal | recessive | embryonic stage phenotype of ewg2

      (Haussmann et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Hsap\NRF1elav.PH is a non-suppressor of lethal - all die during embryonic stage phenotype of ewg2

      (Haussmann and Soller, 2010)
      Other
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hsap\NRF1elav.PH is a suppressor of NMJ bouton phenotype of ewg2

      (Haussmann et al., 2008)

      Hsap\NRF1elav.PH is a suppressor of embryonic/larval neuromuscular junction phenotype of ewg2

      (Haussmann et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The increase in bouton number seen at the larval neuromuscular junctions of ewg2 motorneurons is completely rescued by Hsap\NRF1elav.PH.

      ewg2 animals expressing Hsap\NRF1elav.PH develop to pharate adults, but fail to hatch.

      (Haussmann et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\NRF1elav.PH
      Name Synonyms
      embryonic lethal abnormal vision promoter construct of Haussmann
      Secondary FlyBase IDs
        References (2)