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General Information
Symbol
Dmel\ykiJF03119
Species
D. melanogaster
Name
FlyBase ID
FBal0244933
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing ykiJF03119 under the control of Scer\GAL4tin.CΔ4 have increased ventricular diameters at the end of systole and diastole and a reduction in fractional shortening compared with controls. The heart walls are thinner compared with controls but cardiomyocyte number is the same as in controls. Average cardiomyocyte ploidy is unaffected.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of ykiJF03119 suppresses the cardiac hypertrophy seen in flies expressing Hsap\RAF1gof.Scer\UAS under the control of Scer\GAL4tin.CΔ4, returning the ventricular diameter at the end of diastole (EDD) and heart wall thickness to control levels. The cardiomyocytes abnormalities are partially suppressed.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ykiJF03119
Name Synonyms
Secondary FlyBase IDs
    References (7)