FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4NP3212
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General Information
Symbol
Scer\GAL4NP3212
Species
S. cerevisiae
Name
FlyBase ID
FBal0245080
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}NP3212
Carried in Construct
Also Known As
NP3212, NP3212-GAL4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}NP3212
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        adult stage
        mushroom body output neuron 3
        (Flybrain Neuron Database et al., 2018.6.28, Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body beta' lobe slice 2
        (Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body beta' anterior-posterior layer
        (Tanaka et al., 2008)
        mushroom body beta' middle layer
        (Tanaka et al., 2008)
        mushroom body medial lobe arborizing neuron 5
        (Flybrain Neuron Database et al., 2018.6.28, Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body output neuron 1
        (Flybrain Neuron Database et al., 2018.6.28, Shuai et al., 2015, Tanaka et al., 2008)
        mushroom body gamma lobe slice 5
        (Shuai et al., 2015, Tanaka et al., 2008)
        adult brain | restricted
        (Shuai et al., 2015)
        mushroom body extrinsic neuron
        (Shuai et al., 2015)
        mushroom body gamma lobe slice 3
        (Shuai et al., 2015)
        Additional Information
        Statement
        Reference

        ScerGAL4NP3212 drives expression in mushroom body extrinsic neurons, including mushroom body medial lobe arborizing neurons 4, 5, and 6, that innervate mushroom body gamma lobe slices 3 and 5, and mushroom body beta' lobe slice 2.

        (Shuai et al., 2015)

        Beta' lobe expression has only been mapped for medial lobe arborizing neuron 4, as the arborization patterns of medial lobe arborizing neuron 5 and 6 have not yet been fully characterized. Gamma lobe segment 5 expression is found only with medial lobe arborizing neuron 6.

        (Tanaka et al., 2008)
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4NP3212 cells in adults does not affect startle-induced climbing behavior, compared to controls.

        Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4NP3212 cells in adults significantly reduces startle-induced climbing behavior, compared to controls.

        (Sun et al., 2018)

        Inhibition (using shi1.UAS at 33[o]C) of Scer\GAL4NP3212 cells in adults during testing significantly reduces medium term (3 h) aversive olfactory memory, including its anaesthesia-resistant component, compared to controls; inhibition during and after testing (excluding the memory test) does not affect medium term (3 h) aversive olfactory memory, compared to controls; inhibition does not affect olfactory acuity, compared to controls; inhibition of a subset of Scer\GAL4NP3212 cells in adults (restricted using Scer\GAL80Mef2.mb247) during testing also significantly reduces medium term (3 h) aversive olfactory memory, compared to controls.

        (Bouzaiane et al., 2015)

        Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4NP3212 neurons, in combination with a Gal80[ts] transgene to restrict expression to 1 day prior to training and testing, does not affect 3 hour aversive olfactory memory, compared to controls.

        (Shuai et al., 2015)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Scer\GAL4NP3212
        Name Synonyms
        Secondary FlyBase IDs
          References (6)