FlyBase Allele Report: Dmel\Pex2[UAS.mCherry]

General Information

Symbol

Dmel\Pex2^UAS.mCherry

Species

D. melanogaster

Name

FlyBase ID

FBal0245127

Feature type

allele

Associated gene

Dmel\Pex2

Associated Insertion(s)

Carried in Construct

P{UAS-pex2-mCherry}

Key Links

Transgenic product class

wild_type

(Chen et al., 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Chen et al., 2010)

Mutagen

in vitro construct

(Chen et al., 2010)

Progenitor genotype

Carried in construct

P{UAS-pex2-mCherry}

Cytology

Description

UASt regulatory sequences drive expression of Pex2 sequences fused at the C-terminal end with mCherry.

(Chen et al., 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Pex2

Tagged with

mCherry

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of male sterile phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of abnormal developmental rate phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of abnormal cytokinesis phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of abnormal meiotic cell cycle phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of male sterile phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of abnormal developmental rate phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of abnormal cytokinesis phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of abnormal meiotic cell cycle phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of male sterile phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of abnormal developmental rate phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of abnormal cytokinesis phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of abnormal meiotic cell cycle phenotype of Pex10¹⁰

(Chen et al., 2010)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10⁷

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry is a non-suppressor of spermatid phenotype of Pex10¹⁰

(Chen et al., 2010)

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry is a non-suppressor of testis phenotype of Pex10¹⁰

(Chen et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of pex2^{Scer\UAS.T:Disc\RFP-mCherry} under the control of Scer\GAL4^nos.PG, Scer\GAL4^Hsp83.PA or Scer\GAL4^ptc-559.1 fails to suppress the male sterility and spermatocyte developmental phenotypes associated with pex10⁷ or pex10¹⁰ mutants.

(Chen et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^nanos.PG/Pex2^UAS.mCherry rescues Pex2^HP35039

(Chen et al., 2010)

Scer\GAL4^Hsp83.PA/Pex2^UAS.mCherry rescues Pex2^HP35039

(Chen et al., 2010)

Fails to rescue

Scer\GAL4^ptc-559.1/Pex2^UAS.mCherry fails to rescue Pex2^HP35039

(Chen et al., 2010)

Comments

The male sterility found in pex2^HP35039 can be rescued through expression of pex2^{Scer\UAS.T:Disc\RFP-mCherry} under the control of Scer\GAL4^nos.PG or Scer\GAL4^Hsp83.PA. Expression under the control of Scer\GAL4^ptc-559.1 fails to rescue.

(Chen et al., 2010)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Pex2^{Scer\UAS.T:Disc\RFP-mCherry}

Pex2^UAS.mCherry

pex2^{Scer\UAS.T:Disc\RFP-mCherry}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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