FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tumΔNLS.UAS
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General Information
Symbol
Dmel\tumΔNLS.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0245150
Feature type
allele
Associated gene
Dmel\tum
Associated Insertion(s)
Carried in Construct
P{UAS-tum.ΔNLS}
Key Links
Transgenic product class
inframe_deletion
(Jones et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Jones et al., 2010)
Mutagen
in vitro construct
(Jones et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-tum.ΔNLS}
Cytology
Description

UASt regulatory sequences drive expression of a mutant form of tum lacking a nuclear localization signal.

(Jones et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
tum
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of tumΔNLS.Scer\UAS driven by Scer\GAL4arm.PS is unable to block the cell-fate transformation induced by armS10.Scer\UAS.T:Hsap\MYC expression.

      (Jones et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      tumΔNLS.UAS/Scer\GAL4e22c fails to rescue tumAR2

      (Jones et al., 2010)
      Comments

      Expression of tumΔNLS.Scer\UAS driven by Scer\GAL4e22c fails to rescue the epidermal pattern defects of tumAR2 mutants.

      (Jones et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      tumΔNLS.Scer\UAS
      tumΔNLS.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)