FlyBase Allele Report: Dmel\Su(z)12[JF01706]

General Information

Symbol

Dmel\Su(z)12^JF01706

Species

D. melanogaster

Name

FlyBase ID

FBal0245906

Feature type

allele

Associated gene

Dmel\Su(z)12

Associated Insertion(s)

Carried in Construct

P{TRiP.JF01706}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2008)

Mutagen

in vitro construct

(Ni et al., 2008)

Progenitor genotype

Carried in construct

P{TRiP.JF01706}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Ni et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF01706

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates brain cancer

modeled by pros^JF02308

(Gaultier et al., 2022)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | male, with Scer\GAL4^C587

(Eun et al., 2014)

lethal, with Scer\GAL4^Act5C.PI

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^en.PU

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

Phenotype Manifest In

antenna, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

anterior crossvein, with Scer\GAL4^en.PU

(Dietz et al., 2015)

anterior crossvein, with Scer\GAL4^nub.PK

(Dietz et al., 2015)

cyst progenitor cell | increased number, with Scer\GAL4^C587

(Eun et al., 2014)

eye, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

wing, with Scer\GAL4^en.PU

(Dietz et al., 2015)

wing blade, with Scer\GAL4^en.PU

(Dietz et al., 2015)

Detailed Description

Statement

Reference

Expression of Su(z)12^JF01706 results in: deformed eyes and occasional antenna-to-leg transformations (with the Scer\GAL4^ey.PH driver), occasional loss of anterior crossvein (with Scer\GAL4^nub.PK), blistered wings with missing anterior crossvein at 25[o]C - no phenotype observed at 18[o]C (with Scer\GAL4^en.PU). Scer\GAL4^Act5C.PI-driven expression is pupal lethal; no overt adult phenotype is seen with the Scer\GAL4^GMR.PF driver.

(Dietz et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, Su(z)12^JF01706 has visible | adult stage phenotype, enhanceable by htt^int

(Dietz et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, Su(z)12^JF01706 has wing blade phenotype, enhanceable by htt^int

(Dietz et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

The wing phenotype observed in adult flies expressing Su(z)12^JF01706 under the control of Scer\GAL4^en.PU is weakly enhanced by combination with htt^int.

(Dietz et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

31191

y¹ v¹; P{TRiP.JF01706}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Su(z)12^JF01706

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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