FB2026_02 , released June 18, 2026
Allele: Dmel\drkhs.PM
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General Information
Symbol
Dmel\drkhs.PM
Species
D. melanogaster
Name
heat shock promoter construct of Moressis
FlyBase ID
FBal0246431
Feature type
allele
Associated gene
Dmel\drk
Associated Insertion(s)
Carried in Construct
P{hs-drk.M}
Key Links
Transgenic product class
wild_type
(Moressis et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Moressis et al., 2009)
Mutagen
in vitro construct
(Moressis et al., 2009)
Progenitor genotype
Carried in construct
P{hs-drk.M}
Cytology
Description

A Hsp70 promoter drives drk expression.

(Moressis et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
drk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      drkhs.PM induction does not result in deficits or improvements in learning, or changes in sensorimotor behaviors.

      (Moressis et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      drkhs.PM rescues drkΔP24

      (Moressis et al., 2009)

      drkhs.PM rescues drke0A

      (Moressis et al., 2009)
      Comments

      Learning and 90 minute memory in drkhs.PM-bearing drkΔP24/+ or drke0A heterozygous mutants is indistinguishable from wild-type after activation of the transgene.

      (Moressis et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      drkhs.PM
      Name Synonyms
      heat shock promoter construct of Moressis
      Secondary FlyBase IDs
        References (1)