FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\soloN.UASp.Venus
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General Information
Symbol
Dmel\soloN.UASp.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0246482
Feature type
allele
Associated gene
Dmel\solo
Associated Insertion(s)
Carried in Construct
P{UASp-Venus-solo}
Also Known As
UASp-Venus::SOLO
Key Links
Transgenic product class
wild_type
(Yan et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Yan et al., 2010)
Mutagen
in vitro construct
(Yan et al., 2010)
Progenitor genotype
Carried in construct
P{UASp-Venus-solo}
Cytology
Description

UASp regulatory sequences drive expression of the solo coding region and 3' untranslated region. The protein is tagged at the N-terminal end with Venus.

(Yan et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
solo
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | male
      spermatogonium
      (Yan et al., 2010)
      spermatocyte

      Comment: early prophase I to metaphase II

      (Yan et al., 2010)
      adult stage | female
      germarium
      (Yan et al., 2010)
      epitope tag
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage | female
      germarium | posterior
      (Yan and McKee, 2013)
      oocyte
      (Yan and McKee, 2013)
      nurse cell
      (Yan and McKee, 2013)
      presumptive oocyte
      (Yan and McKee, 2013)
      presumptive nurse cell
      (Yan and McKee, 2013)
      Additional Information
      Statement
      Reference

      solo is expressed in mitotic cells in the posterior region of the germarium, but not in the anterior-most region of the germarium that contains stem cells and early cystoblasts.

      (Yan and McKee, 2013)

      solo foci were seen in nuclei of spermatocytes of all stages up to and including metaphase II but were absent at anaphase II and subsequent stages.

      (Yan et al., 2010)
       
      Marker for
      Reflects expression of
      solo
      (Yan and McKee, 2013, Yan et al., 2010)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4VP16.nanos.UTR/soloN.UASp.Venus rescues soloZ2-0198

      (Yan and McKee, 2013)
      Comments

      The chromosome nondisjunction phenotype seen in soloZ2-0198/Df(2L)A267 females is fully rescued by expression of soloN.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4nos.UTR.T:Hsim\VP16.

      (Yan and McKee, 2013)

      Expression of soloN.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 almost completely rescues the meiotic phenotypes of solounspecified mutants.

      (Yan et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      soloN.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus
      soloN.UASp.Venus
      vasN.solo.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (3)