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General Information
Symbol
Scer\GAL43A
Species
S. cerevisiae
Name
FlyBase ID
FBal0246741
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Gal4-3A, 3A-Gal4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GawB}3A
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    Expression of Scer\GAL43A was observed strongly in 6 vertical system (VS) neurons which, along with the three horizontal system cells, stood out from the surrounding fluorescence. Using MARCM, four VS neurons were specifically labelled.

    <e> debs <t> A <a> vertical system neuron <s><note>

    <e> debs <t> A <a> horizontal system neuron <s><note>

    <e> debs <t> A <a> neuron &&of adult protocerebrum | subset <s><note>

    Scer\GAL43A is expressed in a subset of neurons of the adult protocerebrum, including the horizontal and vertical system neurons.

     
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Optogenetic activation (using Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus with 617 nm (red) light) of Scer\GAL43A cells in adults during the day significantly reduces daytime sleep and significantly increases nighttime sleep following this activation, unlike controls; activation results in a significant reduction in daytime sleep bout duration, with no effect on sleep bout number, compared to baseline, with no effect on nighttime sleep bouts following activation.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Scer\GAL43A
    Name Synonyms
    Secondary FlyBase IDs
      References (4)