FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gishUAS.cTa
Open Close
General Information
Symbol
Dmel\gishUAS.cTa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Tan
FlyBase ID
FBal0246854
Feature type
allele
Associated gene
Dmel\gish
Associated Insertion(s)
Carried in Construct
P{UAS-gish.T}
Key Links
Transgenic product class
cDNA
(Tan et al., 2010)
wild_type
(Tan et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Tan et al., 2010)
wild_type
(Tan et al., 2010)
Mutagen
in vitro construct
(Tan et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-gish.T}
Cytology
Description

UAS regulatory sequences drive expression of a gish cDNA which represents the gish "long" transcription unit (the cDNA utilizes the first transcriptional initiation site and has two extra exons in the 3' region of the gene compared to previously described forms).

(Tan et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
gish
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4Mef2.247/gishUAS.cTa partially rescues gishMB896

      (Tan et al., 2010)

      Scer\GAL4238Y/gishUAS.cTa partially rescues gishMB896

      (Tan et al., 2010)
      Fails to rescue

      Scer\GAL4c305a/gishUAS.cTa fails to rescue gishMB896

      (Tan et al., 2010)

      gishUAS.cTa/Scer\GAL4c739 fails to rescue gishMB896

      (Tan et al., 2010)
      Comments

      Expression of gishScer\UAS.cTa under the control of either Scer\GAL4Mef2.247 or Scer\GAL4238Y partially rescues the 3 minute memory impairment of gishMB896 homozygotes after olfactory associative training.

      Expression of gishScer\UAS.cTa under the control of either Scer\GAL4c305a or Scer\GAL4c739 does not rescue the 3 minute memory impairment of gishMB896 homozygotes after olfactory associative training.

      Experiments in which the temperature-sensitive Scer\GAL80ts.αTub84B allele is used to restrict Scer\GAL4 expression to particular developmental stages by using temperature shifts show that expression of gishScer\UAS.cTa under the control of either Scer\GAL4Mef2.247 or Scer\GAL4238Y only during the adult stage partially rescues the memory impairment of gishMB896 homozygotes after olfactory conditioning, but that expression of gishScer\UAS.cTa under the control of either Scer\GAL4Mef2.247 or Scer\GAL4238Y only during development (prior to the adult stage) does not rescue the memory impairment of gishMB896 homozygotes.

      (Tan et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      gishScer\UAS.cTa
      gishUAS.cTa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Tan
      Secondary FlyBase IDs
        References (1)