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General Information
Symbol
Dmel\Mt2genTG.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0246945
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Genomic fragment containing Mt2 which has been tagged with EGFP.

Genomic fragment that encompasses 300bp upstream of the Mt2 start site and 150bp downstream of the stop codon.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
testis

Comment: NOT hub cell of testis, NOT spermatozoon

testis
nucleus

Comment: NOT hub cell of testis, NOT spermatozoon

Additional Information
Statement
Reference

The Mt2genTG.T:Avic\GFP-EGFP protein is enriched in the cytoplasm of ovaries in a homogenous distribution. Its distribution changes to a granular pattern upon heat shock.

The Mt2genTG.T:Avic\GFP-EGFP protein is ubiquitously expressed throughout development, including most stages of gametogenesis, but not in mature sperm or the hub cell of the testis.

At the subcellular level, the Mt2genTG.T:Avic\GFP-EGFP protein is mostly cytoplasmic, with some present in the nucleus. In early embryos, the cytoplasmic enrichment of Mt2genTG.T:Avic\GFP-EGFP occurs at interphase, but the protein redistributes around nuclear structures during mitosis.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of Mt2genTG.T:Avic\GFP-EGFP rescues the increased lethality seen in Mt299 mutant flies in response to Drosophila C Virus(DCV) infection.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Dnmt2genTG-EGFP
Mt2genTG.EGFP
Mt2genTG.T:Avic\GFP-EGFP
Name Synonyms
Secondary FlyBase IDs
    References (3)