FlyBase Allele Report: Dmel\dl[UAS.GFP]

General Information

Symbol

Dmel\dl^UAS.GFP

Species

D. melanogaster

Name

FlyBase ID

FBal0247019

Feature type

allele

Associated gene

Dmel\dl

Associated Insertion(s)

Carried in Construct

P{UAS-dl.GFP}

Key Links

Transgenic product class

wild_type

(Bettencourt et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Bettencourt et al., 2004)

Mutagen

in vitro construct

(Bettencourt et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-dl.GFP}

Cytology

Description

UASt regulatory sequences drive expression of Dl tagged at the 5' end with GFP.

(Bettencourt et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | third instar larval stage, with Scer\GAL4^Bx-MS1096

(Liu et al., 2015)

Phenotype Manifest In

embryonic/larval crystal cell | cell non-autonomous | larval stage | somatic clone

(Gueguen et al., 2013)

hemocyte | third instar larval stage, with Scer\GAL4^Bx-MS1096

(Liu et al., 2015)

lamellocyte | cell non-autonomous | larval stage | somatic clone | increased number

(Gueguen et al., 2013)

Detailed Description

Statement

Reference

The expression of dl^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^Bx-MS1096 does not induce apoptosis in the third instar larval wing pouch.

Expression of dl^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^Bx-MS1096 results in increased numbers of hemocytes on the surface of third instar larval wing discs, as compared to controls.

(Liu et al., 2015)

Larval lymph glands containing clones expressing dl^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^Act.PU show a reduction in crystal cells and an increase in lamellocytes compared to glands containing control cells. In both cases, mature cells are outside the clone boundary, indicating a non cell-autonomous effect.

(Gueguen et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

dl^UAS.GFP/Scer\GAL4^Bx-MS1096 is an enhancer of increased cell death | third instar larval stage phenotype of Scer\GAL4^Bx-MS1096, vtd^GL00522

(Liu et al., 2015)

Phenotype Manifest In

Enhancer of

Statement

Reference

dl^UAS.GFP/Scer\GAL4^Bx-MS1096 is an enhancer of wing pouch | third instar larval stage phenotype of Scer\GAL4^Bx-MS1096, vtd^GL00522

(Liu et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expressing vtd^GL00522 and dl^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^Bx-MS1096 (together with Dicer-2, for efficient vtd RNAi) leads to a significant increase in apoptosis in the third instar larval wing pouch.

(Liu et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dl^{Scer\UAS.T:Avic\GFP}

dl^UAS.GFP

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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