FlyBase Allele Report: Dmel\sax[A-K382D.UAS]

General Information

Symbol

Dmel\sax^A-K382D.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0247652

Feature type

allele

Associated gene

Dmel\sax

Associated Insertion(s)

Carried in Construct

P{UAS-sax.A-K382D}

Key Links

Transgenic product class

missense_variant

(Haerry, 2010)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Haerry, 2010)

Mutagen

in vitro construct

(Haerry, 2010)

Progenitor genotype

Carried in construct

P{UAS-sax.A-K382D}

Cytology

Description

UAS regulatory sequences drive expression of an activated form of sax which carries a lysine to aspartic acid substitution at position 382.

(Haerry, 2010)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

sax

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^A9/sax^A-K382D.UAS is an enhancer of visible phenotype of Scer\GAL4^A9, tkv^{1-A-T318D.UAS}

(Haerry, 2010)

NOT Enhancer of

Statement

Reference

Scer\GAL4^A9/sax^A-K382D.UAS is a non-enhancer of visible phenotype of Scer\GAL4^A9, tkv^{1-A-T485D.UAS}

(Haerry, 2010)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^A9/sax^A-K382D.UAS is an enhancer of wing phenotype of Scer\GAL4^A9, tkv^{1-A-T318D.UAS}

(Haerry, 2010)

NOT Enhancer of

Statement

Reference

Scer\GAL4^A9/sax^A-K382D.UAS is a non-enhancer of wing vein phenotype of Scer\GAL4^A9, tkv^{1-A-T485D.UAS}

(Haerry, 2010)

Other

Statement

Reference

Scer\GAL4^A9, sax^A-K382D.UAS, tkv^{1-A-T318D-T485D.UAS} has wing vein phenotype

(Haerry, 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of sax^{A-K382D.Scer\UAS} in animals expressing tkv^{1-A-T318D.Scer\UAS} under the control of Scer\GAL4^A9 enhances the wing phenotype.

Expression of sax^{A-K382D.Scer\UAS} in animals expressing tkv^{1-A-T485D.Scer\UAS} under the control of Scer\GAL4^A9 does not enhance the wing vein phenotype.

Expression of sax^{A-K382D.Scer\UAS} in animals expressing tkv^{1-A-T318D-T485D.Scer\UAS} under the control of Scer\GAL4^A9 results in a wing phenotype similar to co-expression with the single mutant tkv^{1-A-T485D.Scer\UAS}.

(Haerry, 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sax^{A-K382D.Scer\UAS}

sax^A-K382D.UAS

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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