FB2026_02 , released June 18, 2026
Allele: Dmel\stairdtp
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General Information
Symbol
Dmel\stairdtp
Species
D. melanogaster
Name
FlyBase ID
FBal0248045
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

The copia element is inserted in the open reading frame of stai.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous stairdtp mutant larvae exhibit a posterior paralysis "tail flip" phenotype. When they crawl along the surface of a substrate they exhibit a crawling behaviour in which the posterior body segments sharply flip upward after each peristaltic wave of muscle contraction during the crawling cycle.

stairdtp/staiB200 mutant larvae exhibit a posterior paralysis "tail flip" phenotype. When they crawl along the surface of a substrate they exhibit a crawling behaviour in which the posterior body segments sharply flip upward after each peristaltic wave of muscle contraction during the crawling cycle.

Homozygous stairdtp mutant larvae are inviable past the third instar larvae stage. No adult progeny are recovered.

A significant number of viable adults are observed in stairdtp/Df(2L)Exel6015 mutants.

A bang-sensitive phenotype is seen in stairdtp/+ adults. The bang-sensitive phenotype is first observed in stairdtp/+ mutant flies at 42 days, with 25% of flies exhibiting the phenotype with mean recovery time of 56 seconds. By 56 days this increases to 58% with an increase in the recovery period to 85.6 seconds.

rdtp5 is homozygous lethal and exhibits a dominant "tail-flipping" phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of staitub.PB partially rescues the phenotypes seen in homozygous stairdtp mutants. The posterior paralysis "tail-flip" phenotype is rescued, but the lethality is not.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

The lethality of this allele is thought to be caused by a second site insertion.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)