FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-let7UAS.cGa
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General Information
Symbol
Dmel\mir-let7UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Gehrke
FlyBase ID
FBal0249352
Feature type
allele
Associated gene
Dmel\mir-let7
Associated Insertion(s)
Carried in Construct
P{UAS-mir-let7.pre}
Key Links
Transgenic product class
wild_type
(Gehrke et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Gehrke et al., 2010)
Mutagen
in vitro construct
(Gehrke et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-mir-let7.pre}
Cytology
Description

UAS regulatory sequences drive expression of a let-7 precursor.

(Gehrke et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-let7
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  Parkinson's disease
      modeled by LrrkI1915T.UAS
      (Gehrke et al., 2010)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Overexpression of let-7Scer\UAS.cGa partly suppresses the dopaminergic neuronal phenotypes of LrrkI1915T.Scer\UAS-expression via Scer\GAL4ple.PF.

      (Gehrke et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      let-7Scer\UAS.cGa
      let-7UAS.cGa
      mir-let7UAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Gehrke
      Secondary FlyBase IDs
        References (1)