FB2021_02, released April 13, 2021

Allele: Scer\GAL4Gr10a.3.7

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General Information
Symbol
Scer\GAL4Gr10a.3.7
Species
S. cerevisiae
Name
FlyBase ID
FBal0249468
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Gr10a-GAL4.3.7}
Also Known As
Gr10a-GAL4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Weiss et al., 2011)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{Gr10a-GAL4.3.7}
      Cytology
      Nature of the lesion
      Statement
      Reference

      A 3.7kb Gr10a promoter fragment is fused upstream of sequence encoding a GAL4 driver.

      (Weiss et al., 2011)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      Gr10a
      Encoded product / tool
      GAL4
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron of terminal organ dorsolateral group
      (Kwon et al., 2011)
      larval gnathal ganglion
      (Kwon et al., 2011)
      gustatory receptor neuron B2 of the terminal organ dorsolateral group
      (Apostolopoulou et al., 2016)
      Additional Information
      Statement
      Reference

      Scer\GAL4Gr10a.3.7 drives expression in one gustatory receptor neuron of the larval terminal organ that has its cell body in the dorsal organ ganglion (TO-dorsolateral group). This neuron also expresses Scer\GAL4Gr33a.4.7, Scer\GAL4Gr66a.1.8 and Scer\GAL4Gr32a.3.7.PW.

      (Kwon et al., 2011)
       
      Marker for
      Reflects expression of
      Gr10a
      (Apostolopoulou et al., 2016, Kwon et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 625 nm (red) light) of Scer\GAL4Gr10a.3.7 cells in larvae increases the probability of ending a run and initiating a turn, compared to baseline conditions.

      (van Giesen et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ablation (using hidUAS.cUa and rprUAS.C) of Scer\GAL4Gr10a.3.7 cells in larvae does not affect bitter avoidance, compared to controls.

      (van Giesen et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Gr10a.3.7
      Name Synonyms
      Secondary FlyBase IDs
        References (9)