FB2026_02 , released June 18, 2026
Allele: Scer\GAL4GMR22G11
Open Close
General Information
Symbol
Scer\GAL4GMR22G11
Species
S. cerevisiae
Name
FlyBase ID
FBal0250690
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR22G11-GAL4}
Also Known As
R22G11
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR22G11-GAL4}
Cytology
Description

A 3650 base pair fragment from the flanking non-coding or intronic region of fru is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR22G11
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult antennal lobe | faint | restricted
      (Jenett and Svirskas, 2012.9.24)
      lineage 1 secondary neuron
      (Shepherd et al., 2016)
      adult stage | male
      adult brain | restricted
      (Hoopfer et al., 2015)
      adult fruitless P1 (male) neuron | subset
      (Hoopfer et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR22G11 drives expression in lineage 1 neurons.

      (Shepherd et al., 2016)

      ScerGAL4GMR22G11 is expressed in 19-23 adult fruitless pMP-e (male) neurons and over 500 other neurons in the male brain.

      (Hoopfer et al., 2015)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 29[o]C) of cells expressing Scer\GAL4GMR22G11 in adult males significantly increases aggressive lunging behavior and wing extensions towards other males, compared to controls.

      (Hoopfer et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR22G11
      Name Synonyms
      Secondary FlyBase IDs
        References (4)