FB2026_02 , released June 18, 2026
Allele: Scer\GAL4GMR23F01
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General Information
Symbol
Scer\GAL4GMR23F01
Species
S. cerevisiae
Name
FlyBase ID
FBal0250763
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR23F01-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR23F01-GAL4}
Cytology
Description

A 877 base pair fragment from the flanking non-coding or intronic region of CG13229 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR23F01
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      larval brain | restricted
      (Tastekin et al., 2015)
      larval ventral nerve cord | restricted
      (Tastekin et al., 2015)
      larval gnathal ganglion | restricted
      (Tastekin et al., 2015)
      Kenyon cell | subset

      Comment: larval thorax

      (Tastekin et al., 2015)
      larval thorax | restricted
      (Tastekin et al., 2015)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR23F01 drives expression in 9-18 embryonic/larval subesophageal ganglion neurons, 1-3 neurons in the thorax, 1-3 ventral nerve cord neurons, 0-20 Kenyon cells, 1-3 posterior dorsomedial neurons and 0-1 posterior ventromedial neurons.

      (Tastekin et al., 2015)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Acute optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 625 nm (red) light) of Scer\GAL4GMR23F01 cells in larvae evokes reliable head casts, unlike controls; restriction of the number of activated cells using Scer\GAL80tsh-GAL80 does not alter this phenotype.

      Inhibition (using Ctet\TeTxLCTNT.UAS) of Scer\GAL4GMR23F01 neurons in larvae results in a significant reduction in the time they spend in the vicinity of an appetitive odor, compared to controls; turn frequency is reduced and run length is slightly increased, compared to controls.

      (Tastekin et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR23F01
      Name Synonyms
      Secondary FlyBase IDs
        References (2)