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General Information
Symbol
Scer\GAL4GMR23F01
Species
S. cerevisiae
Name
FlyBase ID
FBal0250763
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 877 base pair fragment from the flanking non-coding or intronic region of CG13229 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Scer\GAL4GMR23F01 drives expression in 9-18 embryonic/larval subesophageal ganglion neurons, 1-3 neurons in the thorax, 1-3 ventral nerve cord neurons, 0-20 Kenyon cells, 1-3 posterior dorsomedial neurons and 0-1 posterior ventromedial neurons.

 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Acute optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 625 nm (red) light) of Scer\GAL4GMR23F01 cells in larvae evokes reliable head casts, unlike controls; restriction of the number of activated cells using Scer\GAL80tsh-GAL80 does not alter this phenotype.

Inhibition (using Ctet\TeTxLCTNT.UAS) of Scer\GAL4GMR23F01 neurons in larvae results in a significant reduction in the time they spend in the vicinity of an appetitive odor, compared to controls; turn frequency is reduced and run length is slightly increased, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4GMR23F01
Name Synonyms
Secondary FlyBase IDs
    References (2)