FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GMR45F08
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General Information
Symbol
Scer\GAL4GMR45F08
Species
S. cerevisiae
Name
FlyBase ID
FBal0252688
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR45F08-GAL4}
Also Known As
R45F08-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR45F08-GAL4}
Cytology
Description

A 3707 base pair fragment from the flanking non-coding or intronic region of pnt is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR45F08
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ablation (using rprUAS.cZa and hidUAS.cZa) of Scer\GAL4GMR45F08 cells, in combination with a Gal80[ts] transgene to restrict expression to a 24 h interval 2 days after hatching, results in larval lethality; prior to death, third instar larvae have increased spacing between central complex primordia and abnormal morphology of the fan-shaped body primordium and of axons in the posterior plexus of the fan-shaped body primordium, compared to controls; later-born secondary axons of the fan-shaped body primordium appear unaffected. Ablation during the embryonic stage results in embryonic lethality.

      (Andrade et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR45F08
      Name Synonyms
      Secondary FlyBase IDs
        References (8)