FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4GMR65D05
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General Information
Symbol
Scer\GAL4GMR65D05
Species
S. cerevisiae
Name
FlyBase ID
FBal0254057
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR65D05-GAL4}
Also Known As
R65D05-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR65D05-GAL4}
Cytology
Description

A 2954 base pair fragment from the flanking non-coding or intronic region of Ast is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR65D05
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage -- pupal stage
      allatostatin A neuron
      (Deveci et al., 2019)
      pupal stage
      adult allatostatin A neuron of superior lateral protocerebrum
      (Deveci et al., 2019)
      adult stage
      proximal medullary amacrine neuron Pm3
      (Nern et al., 2015)
      medulla
      (Ni et al., 2019)
      adult subesophageal zone
      (Ni et al., 2019)
      adult LP neuron
      (Ni et al., 2019)
      neuron of superior lateral protocerebrum
      (Ni et al., 2019)
      Additional Information
      Statement
      Reference

      The reporter labels several regions in the brain, including sensory regions such as the medulla layer of the optical lobe and the subesophageal zone. It also labels three lateral posterior neurons (LPNs) and neurons in the superior lateral protocerebrum that function upstream to the fan-body neurons and are involved in sleep and wake status.

      (Ni et al., 2019)
       
      Marker for
      allatostatin A neuron
      (Deveci et al., 2019)
      Reflects expression of
      AstA
      (Deveci et al., 2019, Ni et al., 2019)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR65D05
      Name Synonyms
      Secondary FlyBase IDs
        References (8)