FlyBase Allele Report: Scer\GAL4[GMR72F11]

General Information

Symbol

Scer\GAL4^GMR72F11

Species

S. cerevisiae

Name

FlyBase ID

FBal0254537

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{GMR72F11-GAL4}

Also Known As

R72F11-GAL4, GMR72F11-GAL4, 72F11-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Pfeiffer et al., 2011.2.9)

Progenitor genotype

Carried in construct

P{GMR72F11-GAL4}

Cytology

Description

A 3200 base pair fragment from the flanking non-coding or intronic region of CG31760 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)

Allele components

Component

Use(s)

Regulatory region(s)

GMR72F11

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

first instar larval stage -- third instar larval stage

larval Basin neuron

(Eschbach et al., 2021)

third instar larval stage

larval Basin-1 neuron

(Ohyama et al., 2015)

larval Basin-2 neuron

(Ohyama et al., 2015)

larval Basin-3 neuron

(Ohyama et al., 2015)

larval Basin-4 neuron

(Ohyama et al., 2015)

larval Basin neuron

(Eschbach et al., 2020, Hu et al., 2017)

Additional Information

Statement

Reference

Marker for

larval Basin neuron

(Eschbach et al., 2021, Eschbach et al., 2020, Hu et al., 2017)

larval Basin-1 neuron

(Ohyama et al., 2015)

larval Basin-2 neuron

(Ohyama et al., 2015)

larval Basin-3 neuron

(Ohyama et al., 2015)

larval Basin-4 neuron

(Ohyama et al., 2015)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | larval stage | chemical conditional, with Ctet\tetX^TNT-LC.UAS

(Lopez-Bellido et al., 2019)

Phenotype Manifest In

Detailed Description

Statement

Reference

Inhibition (using Ctet\tetX^TNT-LC.UAS) of Scer\GAL4^GMR72F11 cells significantly reduces larval escape behavior in response to HCl application, compared to controls.

(Lopez-Bellido et al., 2019)

Activating Scer\GAL4^GMR72F11 neurons triggers rolling behavior in a significant fraction of larvae and inhibiting these neurons significantly decreases rolling in response to bimodal stimulation (activation of Scer\GAL4^ppk.1.9 neurons along with vibration-induced activation of mechanosensory chordotonal neurons).

(Ohyama et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

39786

w¹¹¹⁸; P{GMR72F11-GAL4}attP2

79599

w¹¹¹⁸ P{20XUAS-IVS-CsChrimson.mVenus}attP18; P{GMR72F11-GAL4}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^GMR72F11

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

Open Close