FB2026_02 , released June 18, 2026
Allele: Scer\GAL4GMR83A12
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General Information
Symbol
Scer\GAL4GMR83A12
Species
S. cerevisiae
Name
FlyBase ID
FBal0255384
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR83A12-GAL4}
Also Known As
R83A12-GAL4, R83A12
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR83A12-GAL4}
Cytology
Description

A 3834 base pair fragment from the flanking non-coding or intronic region of CG42796 is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR83A12
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      antennal mechanosensory and motor center | faint | restricted
      (Jenett and Svirskas, 2012.9.24)
      mushroom body output neuron 11
      (Perisse et al., 2016)
      adult gnathal ganglion | restricted
      (Perisse et al., 2016)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR83A12 drives expression in mushroom body pedunculus-medial lobe and vertical lobe arborizing neuron 2 and 6 large neurons with processes confiend to the adult gnathal ganglion.

      (Perisse et al., 2016)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 33[o]C) of Scer\GAL4GMR83A12 cells in adults 30 min before and during testing significantly reduces 30 min, but not 3 h, aversive olfactory memory, compared to controls; this inhibition also significantly reduces 30 min, 3 h and 24 h appetitive olfactory memory in starved flies, compared to controls; inhibition in naive flies also significantly increases avoidance of 3-octanol and 4-methylcyclohexanol, compared to controls.

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 33[o]C) of Scer\GAL4GMR83A12 cells in adults 15 min before and during testing significantly reduces 30 min aversive olfactory memory, compared to controls; activation does not affect 3 h appetitive olfactory memory in starved flies, but does significantly increase appetitive memory in flies that are fed between training and testing, compared to controls; activation in naive flies also significantly decreases avoidance of 3-octanol and 4-methylcyclohexanol, compared to controls.

      (Perisse et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR83A12
      Name Synonyms
      Secondary FlyBase IDs
        References (7)