A 525 base pair fragment from the ppk6 region, including the putative endogenous ppk6 promoter, is fused upstream of sequence encoding a GAL4 driver.
Scer\GAL4GMR57B04 drives expression in a single gustatory receptor neuron of terminal organ distal group and, occasionally, a single gustatory receptor neuron of the hypophysis.
abnormal locomotor behavior | larval stage | conditional, with Cnoc\ChR1::Csub\ChRCsChrimson.IVS.20xUAS.Venus
Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 625 nm (red) light) of Scer\GAL4GMR57B04 cells in larvae increases the probability of ending a run and initiating a turn, compared to baseline conditions.
Ablation (using hidUAS.cUa and rprUAS.C) of Scer\GAL4GMR57B04 cells in larvae significantly increases attraction to bitter compounds and bitter-sucrose mixtures, compared to controls, with no effect on attraction to sucrose alone.