FB2025_05 , released December 11, 2025
Allele: Scer\GAL4GMR57B04
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General Information
Symbol
Scer\GAL4GMR57B04
Species
S. cerevisiae
Name
FlyBase ID
FBal0256379
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR57B04-GAL4}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR57B04-GAL4}
Cytology
Description

A 525 base pair fragment from the ppk6 region, including the putative endogenous ppk6 promoter, is fused upstream of sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR57B04
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage
      gustatory receptor neuron of terminal organ distal group | subset
      (van Giesen et al., 2016)
      larval gustatory receptor neuron of the ventral pharyngeal sense organ | subset
      (van Giesen et al., 2016)
      Additional Information
      Statement
      Reference

      ScerGAL4GMR57B04 drives expression in a single gustatory receptor neuron of terminal organ distal group and, occasionally, a single gustatory receptor neuron of the hypophysis.

      (van Giesen et al., 2016)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 625 nm (red) light) of Scer\GAL4GMR57B04 cells in larvae increases the probability of ending a run and initiating a turn, compared to baseline conditions.

      (van Giesen et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ablation (using hidUAS.cUa and rprUAS.C) of Scer\GAL4GMR57B04 cells in larvae significantly increases attraction to bitter compounds and bitter-sucrose mixtures, compared to controls, with no effect on attraction to sucrose alone.

      (van Giesen et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR57B04
      Name Synonyms
      Secondary FlyBase IDs
        References (5)