FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ciNIG.2125R
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General Information
Symbol
Dmel\ciNIG.2125R
Species
D. melanogaster
Name
FlyBase ID
FBal0257006
Feature type
allele
Associated gene
Dmel\ci
Associated Insertion(s)
Carried in Construct
P{NIG.2125R}
Also Known As
UAS-ci RNAi, Ci RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Terriente-Félix et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Terriente-Félix et al., 2011)
Mutagen
in vitro construct
(Terriente-Félix et al., 2011)
Progenitor genotype
Carried in construct
P{NIG.2125R}
Cytology
Description

UASt regulatory sequences drive expression of a ci RNAi construct.

(Terriente-Félix et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-2125R
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Larvae expressing ciNIG.2125R under the control of Scer\GAL4nab leads to an increase in neuroblast proliferation.

      (Dong et al., 2021)

      Expression of ciNIG.2125R under the control of Scer\GAL4C587 results in in moderate tumorous germaria phenotype.

      (Li et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Suppressor of
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4nab, ciNIG.2125R has neuroblast | larval stage phenotype, non-suppressible by htlλ.lexAop/Ecol\lexAGAD.repo

      (Dong et al., 2021)
      Suppressor of
      Statement
      Reference

      ciNIG.2125R/Scer\GAL4GMR.PU is a suppressor of eye phenotype of Scer\GAL4GMR.PU, ci-3P.UAS.W.Tag:HA, rdxNIG.9924R

      (Gao et al., 2023)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ciNIG.2125R
      ciRNAi
      (Velarde et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (12)