FlyBase Allele Report: Dmel\Ama[HMS00297]

General Information

Symbol

Dmel\Ama^HMS00297

Species

D. melanogaster

Name

FlyBase ID

FBal0257193

Feature type

allele

Associated gene

Dmel\Ama

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00297}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00297}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00297

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates high grade glioma

modeled by Pi3K92E^CAAX.UAS, btl::Egfr^λ.UAS

(Ariss et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | P-stage, with Scer\GAL4^GMR15B03

(Moucaud et al., 2024)

decreased cell number | larval stage, with Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

decreased occurrence of cell division | larval stage, with Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

increased cell death | larval stage, with Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

Phenotype Manifest In

leg disc | larval stage, with Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

myoblast | decreased number | larval stage, with Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

myoblast | P-stage, with Scer\GAL4^GMR15B03

(Moucaud et al., 2024)

tibial levator tendon cell | P-stage, with Scer\GAL4^GMR15B03

(Moucaud et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Ama^HMS00297, Scer\GAL4^GMR32D05 has decreased cell number | larval stage phenotype, non-suppressible by sty^VSH330208, Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

Ama^HMS00297, Scer\GAL4^GMR32D05 has decreased cell number | larval stage phenotype, non-suppressible by rl^Sem.S.UAS, Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

NOT Suppressor of

Statement

Reference

sordd1^UAS.cXa/Ama^HMS00297, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa

(Xu et al., 2020)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Ama^HMS00297, Scer\GAL4^GMR32D05 has myoblast | larval stage | decreased number phenotype, non-suppressible by sty^VSH330208, Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

Ama^HMS00297, Scer\GAL4^GMR32D05 has myoblast | larval stage | decreased number phenotype, non-suppressible by rl^Sem.S.UAS, Scer\GAL4^GMR32D05

(Moucaud et al., 2024)

NOT Suppressor of

Statement

Reference

sordd1^UAS.cXa/Ama^HMS00297, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa

(Xu et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

33416

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00297}attP2

NIG-Fly

HMS00297

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00297}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Ama^HMS00297

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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