FlyBase Allele Report: Dmel\ninaE[G69D.UAS.cXa]

General Information

Symbol

Dmel\ninaE^G69D.UAS.cXa

Species

D. melanogaster

Name

UAS construct a of Xu

FlyBase ID

FBal0364817

Feature type

allele

Associated gene

Dmel\ninaE

Associated Insertion(s)

Carried in Construct

P{UAS-Rh1^G69D.X}

Also Known As

UAS-Rh1^G69D

Key Links

Transgenic product class

missense_variant

(Xu et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Xu et al., 2020)

Mutagen

in vitro construct

(Xu et al., 2020)

Progenitor genotype

Carried in construct

P{UAS-Rh1^G69D.X}

Cytology

Description

UASt regulates expression of ninaE cDNA (RH01460) containing the G69D mutation.

(Xu et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

ninaE

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of retinitis pigmentosa

CEA

(Xie et al., 2021)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | adult stage, with Scer\GAL4^GMR.PU

(Xu et al., 2020)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Xu et al., 2020)

ommatidium | decreased number, with Scer\GAL4^GMR.PU

(Xu et al., 2020)

Detailed Description

Statement

Reference

Expressing ninaE^G69D.UAS.cXa under the control of Scer\GAL4^GMR.PU leads to a glossy eye phenotype, with loss of ommatidia.

(Xu et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sip3^UAS.Tag:MYC/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sordd2^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sordd2^EY20019/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sordd1^G757/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by Smg5^UAS.ORF/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by Hrd3^HMJ23763/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by sip3^HMC02976/sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | somatic clone | adult stage phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, Hrd3^CB-0952-3/Hrd3^CB-0952-3, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | somatic clone | adult stage phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, sip3¹/sip3¹/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by Hsap\RNF5^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible | partially by Hsap\RNF185^GMR.cXa

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, suppressible by Hsap\SYVN1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by Rpn12^HMS01032/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by sordd1^UAS.cXa/TER94^GD9777/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by sordd1^UAS.cXa/Ufd1^GL01251/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by sordd1^UAS.cXa/TER94^JF03402/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by Tsf1^HMC04224/sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by CG9962^HMC05154/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has visible | adult stage phenotype, non-suppressible by sordd1^UAS.cXa/Ama^HMS00297, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by Hsap\SYVN1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by Hsap\RNF5^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible | partially by Hsap\RNF185^GMR.cXa

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by Hsap\SYVN1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible | partially by Hsap\RNF185^GMR.cXa

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by Hsap\RNF5^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sip3^UAS.Tag:MYC/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sip3^UAS.Tag:MYC/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sordd2^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sordd2^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by Smg5^UAS.ORF/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sordd2^EY20019/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sordd1^G757/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sordd2^EY20019/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sordd1^G757/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by Smg5^UAS.ORF/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by Hrd3^HMJ23763/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, suppressible by sip3^HMC02976/sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by sip3^HMC02976/sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | decreased number phenotype, suppressible by Hrd3^HMJ23763/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye | somatic clone phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, sip3¹/sip3¹/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye | somatic clone phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, Hrd3^CB-0952-3/Hrd3^CB-0952-3, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | somatic clone | decreased number phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, sip3¹/sip3¹/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has ommatidium | somatic clone | decreased number phenotype, suppressible by Scer\FLP1^ey.PU/sordd1^UAS.cXa, Hrd3^CB-0952-3/Hrd3^CB-0952-3, Scer\GAL4^GMR.PU

(Xu et al., 2020)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by Rpn12^HMS01032/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd1^UAS.cXa/Ufd1^GL01251/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd1^UAS.cXa/TER94^JF03402/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd1^UAS.cXa/TER94^GD9777/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by Tsf1^HMC04224/sordd1^UAS.cXa/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd1^UAS.cXa/Ama^HMS00297, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by CG9962^HMC05154/sordd1^UAS.cXa, Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd1^C165S.UAS/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sordd2^C165S.UAS/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Scer\GAL4^GMR.PU, ninaE^G69D.UAS.cXa has eye phenotype, non-suppressible by sip3^C327S.UAS/Scer\GAL4^GMR.PU

(Xu et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ninaE^G69D.UAS.cXa

Name Synonyms

UAS construct a of Xu

Secondary FlyBase IDs

References (2)

Report Sections

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