FlyBase Allele Report: Dmel\fj[HMS01310]

General Information

Symbol

Dmel\fj^HMS01310

Species

D. melanogaster

Name

FlyBase ID

FBal0257903

Feature type

allele

Associated gene

Dmel\fj

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01310}

Also Known As

UAS-fj-RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS01310}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01310

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for fj^HMS01310 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to fj^HMS01310 males results in: 75% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

fj^HMS01310, Scer\GAL4^ap-md544 is a non-suppressor of neoplasia | larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544, psq^KK111691

(Fereres et al., 2019)

fj^HMS01310, Scer\GAL4^ap-md544 is a non-suppressor of increased cell number | larval stage phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544, psq^KK111691

(Fereres et al., 2019)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

fj^HMS01310, Scer\GAL4^ap-md544 is a non-suppressor of wing disc phenotype of Egfr^UAS.cBa, Scer\GAL4^ap-md544, psq^KK111691

(Fereres et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

All larvae co-expressing psq^KK111691 and Egfr^UAS.cBa under the control of Scer\GAL4^ap-md544 during larval stages (using Gal80[ts] for the temporal regulation of expression) wing discs tumors, associated with higher numbers of myoblasts. These phenotypes are not suppressed by the co-expression of fj^HMS01310 under the control of Ecol\lexA^GMR15B03.

(Fereres et al., 2019)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

34323