Pan-neuronal NFAT overexpression through Scer\GAL4^elav-C155-driven expression of NFAT^EP19579 results in significantly smaller synapses with clusters of terminal synaptic boutons and an overall reduction in the expanse of the pre-synaptic arbor.

Post-synaptic muscle expression of NFAT^EP19579 under the control of Scer\GAL4^Mef2.PR has no observable effect on neuromuscular junction size.

Expression of NFAT^EP19579 under the control of Scer\GAL4^D42 results in neuromuscular junctions with reduced synapse length compared to controls.

Neuronal expression of NFAT^EP1508 (under the control of Scer\GAL4^elav-C155) reduces transmitter release (mean EJC amplitude) while spontaneous mini EJCs are unaffected. The number of active zones are not affected in these mutants.

Overexpression of NFAT^EP19579 in RP2 neurons under the control of Scer\GAL4^{shakB.lethal.4.1} dramatically reduces the excitability of RP2, in that the input resistance is reduced to half of the wild-type. As a consequence of this drastic increase in the leakiness of the cell NFAT neurons depolarize much less, and produce fewer action potentials than controls.

Larve expressing NFAT^EP19579 pan-neuronally (under the control of Scer\GAL4^elav-C155) move significantly slower than control animals and thus cover a smaller distance in an allotted time. Moreover, as compared to a relatively straight trajectory in wild-type animals, NFAT^EP1508-expressing larvae also display a greater degree of turning and 'rolling'.

Expression of NFAT^EP19579, driven by Scer\GAL4^OK6 in an otherwise wild-type background results in a slightly reduced neuromuscular junction size.

NFAT^EP19579 has abnormal neuroanatomy phenotype, suppressible by futsch^N94/futsch[+]

NFAT^EP19579, Scer\GAL4^Toll-6-D42 has synapse phenotype, suppressible by futsch^N94/futsch[+]

Scer\GAL4^RapGAP1-OK6/NFAT^EP19579 is a suppressor of synapse phenotype of SERCA^Kum170, comt⁶