FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sox14L1
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General Information
Symbol
Dmel\Sox14L1
Species
D. melanogaster
Name
FlyBase ID
FBal0260619
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

Genomic sequence encompassing the first exon of Sox14 plus 400bp upstream of the promoter has been replaced by a loxP cassette containing a mini-w marker.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous and Sox14L1/Df(2R)BSC136 animals die either as early prepupae (37% and 41%), with defects in anterior spiracle eversion and other morphological defects, as pupae (26% and 26%) that are often cryptocephalic with a failure of the legs and wings to elongate properly, and often show a failure to tan, or as pharate adults (37% and 33%) which show similar phenotypes to animals dying at earlier stages as well as a pinhead phenotype. In most cases, terminal differentiation of the abdomen is not seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)