FlyBase Allele Report: Dmel\Gcn2[GL00267]

General Information

Symbol

Dmel\Gcn2^GL00267

Species

D. melanogaster

Name

FlyBase ID

FBal0262737

Feature type

allele

Associated gene

Dmel\Gcn2

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00267}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.GL00267}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-GL00267

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.nanos.UTR}, Scer\GAL4^VP16.otu, Scer\GAL4^nanos.PG

(Sopko et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for Gcn2^GL00267 and MTD-Gal4 (consists of Scer\GAL4^{otu.T:Hsim\VP16}, Scer\GAL4^nos.PG and Scer\GAL4^{nos.UTR.T:Hsim\VP16}) crossed to Gcn2^GL00267 males results in: 95% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Gcn2^GL00267, Scer\GAL4^elav.PU is a suppressor | partially of abnormal developmental rate phenotype of ProRS-m^VSH330525, Scer\GAL4^elav.PU

(Xu et al., 2026)

Gcn2^GL00267, Scer\GAL4^elav.PU is a suppressor | partially of bang sensitive phenotype of ProRS-m^VSH330525, Scer\GAL4^elav.PU

(Xu et al., 2026)

NOT Suppressor of

Statement

Reference

Gcn2^GL00267, Scer\GAL4^109(2)80 is a non-suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Scer\GAL4^109(2)80, prel^UAS.Tag:HA

(Tsuyama et al., 2017)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Gcn2^GL00267, Scer\GAL4^109(2)80 is a non-suppressor of abdominal dorsal multidendritic neuron ddaC | third instar larval stage phenotype of Scer\GAL4^109(2)80, prel^UAS.Tag:HA

(Tsuyama et al., 2017)

Gcn2^GL00267, Scer\GAL4^109(2)80 is a non-suppressor of dendrite | third instar larval stage phenotype of Scer\GAL4^109(2)80, prel^UAS.Tag:HA

(Tsuyama et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The shortening of the dendritic arbor in class IV ddaC neurons in third instar larvae expressing prel^{Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^109(2)80 is not significantly affected by co-expression of Gcn2^GL00267.

(Tsuyama et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

35355

y¹ sc^* v¹ sev²¹; P{TRiP.GL00267}attP2

NIG-Fly

GL00267

y¹ sc^* v¹ sev²¹; P{TRiP.GL00267}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gcn2^GL00267

Gcn2[GL]

(Tsuyama et al., 2017)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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