FlyBase Allele Report: Dmel\ProRS-m[VSH330525]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\ProRS-m^VSH330525

General Information

Symbol

Dmel\ProRS-m^VSH330525

Species

D. melanogaster

Name

FlyBase ID

FBal0339943

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

Transgenic product class

(Meadows, 2018.4.4)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Meadows, 2018.4.4)

Mutagen

in vitro construct

(Meadows, 2018.4.4)

Progenitor genotype

Carried in construct

Cytology

Description

UAS regulatory sequences drive expression of a short hairpin microRNA (shRNA).

(Meadows, 2018.4.4)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

dsRNA-VSH330525

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate, with Scer\GAL4^da.PU

(Xu et al., 2026)

abnormal developmental rate, with Scer\GAL4^elav.PU

(Xu et al., 2026)

bang sensitive, with Scer\GAL4^elav.PU

(Xu et al., 2026)

lethal - all die before end of larval stage, with Scer\GAL4^da.PU

(Xu et al., 2026)

Phenotype Manifest In

adult brain, with Scer\GAL4^elav.PU

(Xu et al., 2026)

mitochondrial crista | adult stage, with Scer\GAL4^elav.PU

(Xu et al., 2026)

mitochondrion | adult stage, with Scer\GAL4^elav.PU

(Xu et al., 2026)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ProRS-m^VSH330525, Scer\GAL4^elav.PU has abnormal developmental rate phenotype, suppressible | partially by Gcn2^GL00267, Scer\GAL4^elav.PU

(Xu et al., 2026)

ProRS-m^VSH330525, Scer\GAL4^elav.PU has bang sensitive phenotype, suppressible | partially by Gcn2^GL00267, Scer\GAL4^elav.PU

(Xu et al., 2026)

ProRS-m^VSH330525, Scer\GAL4^elav.PU has abnormal developmental rate phenotype, suppressible | partially by crc^JF02007, Scer\GAL4^elav.PU

(Xu et al., 2026)

ProRS-m^VSH330525, Scer\GAL4^elav.PU has bang sensitive phenotype, suppressible | partially by crc^JF02007, Scer\GAL4^elav.PU

(Xu et al., 2026)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

ProRS-m^VSH330525 is rescued by Scer\GAL4^da.PU/ProRS-m^UAS.cXa

(Xu et al., 2026)

ProRS-m^VSH330525 is rescued by Scer\GAL4^elav.PU/ProRS-m^UAS.cXa

(Xu et al., 2026)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

v330525

P{VSH330525}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

330525

(Meadows, 2018.4.4)

ProRS-m^VSH330525

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections