FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\aopHMS01256
Open Close
General Information
Symbol
Dmel\aopHMS01256
Species
D. melanogaster
Name
FlyBase ID
FBal0263268
Feature type
allele
Associated gene
Dmel\aop
Associated Insertion(s)
Carried in Construct
P{TRiP.HMS01256}
Also Known As
UAS-yan-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Ni et al., 2011.7.19)
Mutagen
in vitro construct
(Ni et al., 2011.7.19)
Progenitor genotype
Carried in construct
P{TRiP.HMS01256}
Cytology
Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HMS01256
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of aopHMS01256 under the control of Scer\GAL4esg-NP5130 (using tub-Gal80[ts] to limit the time of RNAi expression) does not affect intestinal stem cell growth in the adult midgut.

      (Jin et al., 2015)

      Expression of aopHMS01256 in the adult gut and fat body under the control of Scer\GAL4Switch1.106 (in the presence of RU486) has no major effect on lifespan compared to controls.

      (Alic et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT suppressed by
      Statement
      Reference

      Scer\GAL4da.Switch.PT, aopHMS01256 has short lived | RU486 conditional phenotype, non-suppressible by chico1/chico[+]

      (Slack et al., 2015)
      Suppressor of
      Statement
      Reference

      aopHMS01256, Scer\GAL4Switch1.106 is a suppressor of long lived | RU486 conditional phenotype of Ras85DN17.UAS, Scer\GAL4Switch1.106

      (Slack et al., 2015)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of foxoScer\UAS.cFa and aopHMS01256 in the adult midgut and fat body under the control of Scer\GAL4Switch1.106 (in the presence of RU486) results in a reduced lifespan compared to controls.

      (Alic et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      aopHMS01256
      Name Synonyms
      Secondary FlyBase IDs
        References (8)