Twenty copies of the UAS site drive expression of a Drosophila codon-optimised form of P1cre recombinase that is tagged at the C-terminal end with the Tag:PEST(mOdc) degradation signal.
eye, with Scer\GAL4GMR.PF
Animals expressing P1\cre20xScer\UAS.T:Mmus\PEST1 under the control of Scer\GAL4elav-C155 either do not reach the adult stage or are extremely uncoordinated and short lived.
Animals expressing P1\cre20xScer\UAS.T:Mmus\PEST1 under the control of Scer\GAL4GMR.PF show strong defects in both external eye morphology and the arrangement of cells in the retina.