FB2026_02 , released June 18, 2026
Allele: Dmel\pblΔC-term.UAS.Tag:HA
Open Close
General Information
Symbol
Dmel\pblΔC-term.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0263877
Feature type
allele
Associated gene
Dmel\pbl
Associated Insertion(s)
Carried in Construct
P{UAS-pbl.ΔC-term.HA}
Key Links
Transgenic product class
inframe_deletion
(van Impel et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(van Impel et al., 2009)
Mutagen
in vitro construct
(van Impel et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-pbl.ΔC-term.HA}
Cytology
Description

UASt regulatory sequences drive expression of a mutated form of pbl-RA cDNA (amino acids 1-720) that lacks the C-terminal tail and is tagged at the C-terminal end with Tag:HA.

(van Impel et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pbl
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No defects in early mesodermal development are observed when pblΔC-term.Scer\UAS.T:Ivir\HA1 is expressed under the control of the Scer\GAL4twi.2PE and Scer\GAL4Mef2.PR drivers.

      (van Impel et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      pblΔC-term.UAS.Tag:HA/Scer\GAL4twi.2PE partially rescues pbl3

      (van Impel et al., 2009)
      Fails to rescue

      pblΔC-term.UAS.Tag:HA/Scer\GAL4twi.2PE fails to rescue pbl3

      (van Impel et al., 2009)
      Comments

      Expression of pblΔC-term.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4twi.2PE partially rescues the mesodermal migration defects seen in pbl3 homozygous mutants but is unable to rescue the cytokinesis defects.

      (van Impel et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pblΔC-term.Scer\UAS.T:Ivir\HA1
      pblΔC-term.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)