FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Scer\GAL4Ir40a.3011
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General Information
Symbol
Scer\GAL4Ir40a.3011
Species
S. cerevisiae
Name
FlyBase ID
FBal0264267
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Ir40a-GAL4.3011}
Also Known As
Ir40a-Gal4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Silbering et al., 2011)
Progenitor genotype
Carried in construct
P{Ir40a-GAL4.3011}
Cytology
Description

A 3011bp fragment from immediately upstream of the Ir40a start codon is fused upstream of sequence encoding a GAL4 driver.

(Silbering et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Ir40a
Ir40a_3011bp
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      sensillum of sacculus chamber I
      (Enjin et al., 2016, Silbering et al., 2011)
      neuron of sensillum of sacculus chamber II
      (Silbering et al., 2011)
      adult antennal lobe glomerulus | subset
      (Silbering et al., 2011)
      adult hygrosensory neuron Ir40a
      (Knecht et al., 2016)
      adult hygrosensory neuron Ir40a VP4
      (Sun et al., 2018)
      chamber II of sacculus
      (Sun et al., 2018)
      adult thermosensory neuron
      (Enjin et al., 2016)
      sensillum of sacculus chamber II
      (Enjin et al., 2016)
      neuron of chamber I of sacculus
      (Enjin et al., 2016)
      neuron of chamber II of sacculus
      (Enjin et al., 2016)
      Additional Information
      Statement
      Reference

      This GAL4 line drives expression in hygrosensitive neurons in the second chamber of the sacculus.

      (Sun et al., 2018)

      ScerGAL4Ir40a.3011 is expressed in the neurons that innervate the basiconic and blunt-tipped sensillum of sacculus and in a subset of antennal lobe glomeruli.

      (Silbering et al., 2011)
       
      Marker for
      Reflects expression of
      Ir21a
      (Knecht et al., 2016)
      Ir40a
      (Sun et al., 2018, Silbering et al., 2011)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using Hsap\KCNJ2UAS.EGFP) of Scer\GAL4Ir40a.3011 neurons in adults results in a loss of the increase in heat avoidance displayed by controls when heat is coupled with dry conditions, relative to humid conditions.

      (Frank et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Ir40a.3011
      Name Synonyms
      Secondary FlyBase IDs
        References (18)