FlyBase Allele Report: Dmel\wntD[UASp.cEa]

General Information

Symbol

Dmel\wntD^UASp.cEa

Species

D. melanogaster

Name

FlyBase ID

FBal0265078

Feature type

allele

Associated gene

Dmel\wntD

Associated Insertion(s)

Carried in Construct

P{UASp-wntD.M}

Key Links

Transgenic product class

wild_type

(McElwain et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(McElwain et al., 2011)

Mutagen

in vitro construct

(McElwain et al., 2011)

Progenitor genotype

Carried in construct

P{UASp-wntD.M}

Cytology

Description

UASp regulatory sequences drive expression of wntD.

(McElwain et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

wntD

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | maternal effect, with Scer\GAL4^Act.PU

(McElwain et al., 2011)

Phenotype Manifest In

dendrite, with Scer\GAL4^A58

(Thyagarajan et al., 2025)

larval dorsal multidendritic neuron ddaE, with Scer\GAL4^A58

(Thyagarajan et al., 2025)

microtubule, with Scer\GAL4^A58

(Thyagarajan et al., 2025)

Detailed Description

Statement

Reference

The progeny of females expressing wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU show only a low rate of survival to the pupal stage.

(McElwain et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-enhanceable by Df(3R)Tl-P/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-enhanceable by Df(3R)ME15/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-enhanceable by Df(2R)Np5/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-enhanceable by Df(2R)w45-30n/+

(McElwain et al., 2011)

Suppressed by

Statement

Reference

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by +/Df(3R)L127

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by fz4[+]/fz4^25-1

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by fz4^3-1/fz4[+]

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by fz4[+]/fz4^GS7412

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by Cerk[+]/Cerk^BG01100

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by Df(1)Sxl-bt/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, suppressible by Df(3R)e1025-14/+

(McElwain et al., 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by dsh³

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Cerk[+]/Cerk^X35

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Dgk^f03609/Dgk[+]

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Sk2^KG05894/Sk2[+]

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Df(1)BSC287/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Df(1)BSC288/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Df(1)BSC722/+

(McElwain et al., 2011)

Scer\GAL4^Act.PU, wntD^UASp.cEa has lethal | maternal effect phenotype, non-suppressible by Df(1)ED7067/+

(McElwain et al., 2011)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of fz4^{Scer\UAS.P\T.cMa} under the control of Scer\GAL4^Act.PU suppresses the ability of Df(1)Sxl-bt to suppress the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

One copy of fz4^GS7412, fz4^3-1 or fz4^25-1 suppresses the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

One copy of Cerk^BG01100 suppresses the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

One copy of Cerk^X35 fails to suppress the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

One copy of Dgk^f03609, Sk2^KG05894, Df(1)BSC287, Df(1)BSC288, Df(1)BSC722 or Df(1)ED7067 fails to suppress the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

One copy of Mulk^LL03414 suppresses the maternal effect lethality caused by expression of wntD^{Scer\UAS.P\T.cEa} under the control of Scer\GAL4^Act.PU.

(McElwain et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

38409

w^*; P{UASp-wntD.M}3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

wntD^{Scer\UAS.P\T.cEa}

wntD^UASp.cEa

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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