FlyBase Allele Report: Dmel\skl[UASp.cSa]

General Information

Symbol

Dmel\skl^UASp.cSa

Species

D. melanogaster

Name

FlyBase ID

FBal0265576

Feature type

allele

Associated gene

Dmel\skl

Associated Insertion(s)

Carried in Construct

P{UASp-skl.S}

Key Links

Transgenic product class

wild_type

(Sato et al., 2007)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Sato et al., 2007)

Mutagen

in vitro construct

(Sato et al., 2007)

Progenitor genotype

Carried in construct

P{UASp-skl.S}

Cytology

Description

UASp regulatory sequences drive expression of skl.

(Sato et al., 2007)

Allele components

Component

Use(s)

Regulatory region(s)

UASp

binary expression system - regulatory region

Encoded product / tool

skl

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The amount of pole cell apoptosis seen when skl^{Scer\UAS.P\T.cSa} is expressed under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} is comparable to controls.

(Sato et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has increased cell death | maternal effect | embryonic stage 13 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has increased cell death | maternal effect | embryonic stage 14 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has increased cell death | maternal effect | embryonic stage 15 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has increased cell death | maternal effect | embryonic stage 16 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Enhancer of

Statement

Reference

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of increased cell death | embryonic stage 13 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of increased cell death | embryonic stage 14 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of increased cell death | embryonic stage 15 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of increased cell death | embryonic stage 16 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has primordial germ cell | maternal effect | embryonic stage 13 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has primordial germ cell | maternal effect | embryonic stage 14 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has primordial germ cell | maternal effect | embryonic stage 15 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Scer\GAL4^{VP16.nanos.UTR}, nanos^BN, skl^UASp.cSa has primordial germ cell | maternal effect | embryonic stage 16 phenotype, suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Sato et al., 2007)

Enhancer of

Statement

Reference

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of primordial germ cell | embryonic stage 13 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of primordial germ cell | embryonic stage 14 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of primordial germ cell | embryonic stage 15 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

skl^UASp.cSa/Scer\GAL4^{VP16.nanos.UTR} is an enhancer of primordial germ cell | embryonic stage 16 | maternal effect phenotype of nanos^BN

(Sato et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of skl^{Scer\UAS.P\T.cSa} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} enhances the pole cell apoptosis seen in stage 13-16 embryos derived from nos^BN females.

Removal of zygotic W (W⁰⁵⁰¹⁴/Df(3L)H99) suppresses the pole cell apoptosis seen when skl^{Scer\UAS.P\T.cSa} is expressed under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} in stage 13-16 embryos derived from nos^BN females.

(Sato et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

skl^{Scer\UAS.P\T.cSa}

skl^UASp.cSa

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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