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General Information
Symbol
Dmel\Lkb1UAS.cWa
Species
D. melanogaster
Name
FlyBase ID
FBal0265787
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-LKB1
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a full length Lkb1 cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of lkb1Scer\UAS.cWa under the control of Scer\GAL4GMR.PF has little effect on eye morphology or photoreceptor number.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of lkb1Scer\UAS.cWa enhances the eye degeneration seen when par-1Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4GMR.PF.

Xenogenetic Interactions
Statement
Reference

Expression of lkb1Scer\UAS.cWa enhances the eye phenotypes seen when Hsap\MAPTR406W.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF, resulting in severe disorganisation of the eye and drastic loss of photoreceptor neurons and surrounding cells.

Expression of lkb1Scer\UAS.cWa does not enhance the photoreceptor loss phenotype seen when Hsap\MAPTS2A.Scer\UAS is expressed under the control of Scer\GAL4GMR.PF.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Lkb1Scer\UAS.cWa
Lkb1UAS.cWa
lkb1Scer\UAS.cWa
Name Synonyms
Secondary FlyBase IDs
    References (2)