The HindIII cassette in dshHindIII that contains an endogenous polyglutamine repeat has been replaced with a polyglutamine repeat. This repeat encodes 43Q - R - 65Q.
dshQ108 shows only 24% rescue of the lethality of dsh3 flies. The surviving adults have polarity and patterning defects including notched wings, disordered bristles and bifurcated legs.