FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rh41
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General Information
Symbol
Dmel\Rh41
Species
D. melanogaster
Name
FlyBase ID
FBal0265965
Feature type
allele
Associated gene
Dmel\Rh4
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Nucleotide substitution: C278T.

    (Vasiliauskas D. and Desplan C., 2013.10.3)

    Amino acid replacement: Q46term.

    (Vasiliauskas D. and Desplan C., 2013.10.3)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3L:16,862,335..16,862,335 [-]
    Nucleotide change:

    C16862335T

    Reported nucleotide change:

    C278T

    Amino acid change:

    Q46term | Rh4-PA

    Reported amino acid change:

    Q46term

    Comment:

    The following mutation positions were reported in the paper: Rh31, Q46stop and Rh41, Y203stop. Based on the amino acid sequences of the two proteins, it appears that the two locations were mistakenly switched. Therefore, the Rh41 mutation was mapped as Q46stop.

    Comment:

    The following mutation positions were reported in FBrf0216554 : Rh31, Q46stop and Rh41, Y203stop. The author confirmed that the positions of the two mutations were switched and Rh41 maps to Q46stop.

    (Vasiliauskas D. and Desplan C., 2013.10.3, Vasiliauskas et al., 2011)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
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        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
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        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Temperature preferences of Rh41 homozygous mutant third instar larvae are unchanged compared to wild-type controls.

        (Sokabe et al., 2016)

        Rh41 mutant class IV dendritic arborization neurons do not exhibit any defects in light response.

        (Xiang et al., 2010)
        External Data
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        Complementation and Rescue Data
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        Mutant
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        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        References (9)