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General Information
Symbol
Dmel\lidGL00612
Species
D. melanogaster
Name
FlyBase ID
FBal0266311
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a short inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of lidGL00612 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in female germlines results in sterility and abnormal morphology of the karyosome in most oocytes.

Scer\GAL4nos.PU driven knockdown of lidGL00612 leads to a significant decrease in germline stem cell (GSC) number, a significant increase in average hub area, and a decrease in mitotic activity of GSCs in the testes compared to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of Stat92EScer\UAS.cPa suppresses the germline stem cell loss seen in testes with lidGL00612 driven by Scer\GAL4nos.PU.

Co-expression of Ptp61FHMS00421 suppresses the loss of germline stem cells in testes with lidGL00612 driven by Scer\GAL4nos.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
lidGL00612
Name Synonyms
Secondary FlyBase IDs
    References (4)