FlyBase Allele Report: Dmel\babo[RNAi.a.UAS]

General Information

Symbol

Dmel\babo^RNAi.a.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0267085

Feature type

allele

Associated gene

Dmel\babo

Associated Insertion(s)

Carried in Construct

P{UAS-babo.a.RNAi}

PBac{UAS-babo.a.RNAi}

Also Known As

babo-A miRNA, UAS-baboA-miRNA

Key Links

Transgenic product class

RNAi_reagent

(Awasaki et al., 2011)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Awasaki et al., 2011)

Mutagen

in vitro construct

(Awasaki et al., 2011)

Progenitor genotype

Carried in construct

P{UAS-babo.a.RNAi}

PBac{UAS-babo.a.RNAi}

Cytology

Description

UAS regulatory sequences drive expression of a miRNA construct targeting two 22 nt sequences within the coding region of the 'a' isoform of babo.

(Awasaki et al., 2011)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

babo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | larval stage, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

abnormal neuroanatomy | larval stage, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

decreased body size | adult stage, with Scer\GAL4^da.G32

(Lee et al., 2024)

decreased size | adult stage, with Scer\GAL4^ci.PC

(Upadhyay et al., 2020)

decreased size | adult stage, with Scer\GAL4^NP5130

(Upadhyay et al., 2020)

decreased size | larval stage, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

decreased size | larval stage, with Scer\GAL4^hh-Gal4

(Upadhyay et al., 2020)

decreased size | pharate adult stage, with Scer\GAL4^da.G32

(Lee et al., 2024)

visible | adult stage, with Scer\GAL4^da.G32

(Lee et al., 2024)

Phenotype Manifest In

adult brain | pharate adult stage, with Scer\GAL4^da.G32

(Lee et al., 2024)

adult optic lobe | pharate adult stage, with Scer\GAL4^da.G32

(Lee et al., 2024)

anterior-posterior compartment boundary of the wing disc | larval stage, with Scer\GAL4^hh-Gal4

(Upadhyay et al., 2020)

embryonic/larval optic lobe | larval stage, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

epithelium | larval stage, with Scer\GAL4^hh-Gal4

(Upadhyay et al., 2020)

larval brain, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

neuroblast | larval stage, with Scer\GAL4^GMR31H09

(Lee et al., 2024)

wing, with Scer\GAL4^da.G32

(Lee et al., 2024)

wing, with Scer\GAL4^NP5130

(Upadhyay et al., 2020)

wing anterior compartment, with Scer\GAL4^ci.PC

(Upadhyay et al., 2020)

wing disc posterior compartment | larval stage, with Scer\GAL4^hh-Gal4

(Upadhyay et al., 2020)

wing hair, with Scer\GAL4^ci.PC

(Upadhyay et al., 2020)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

babo^RNAi.a.UAS/Scer\GAL4^NP5130 is a suppressor of increased size | larval stage phenotype of Scer\GAL4^NP5130, Smox^RNAi.UAS.cPa

(Upadhyay et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

babo^RNAi.a.UAS/Scer\GAL4^NP5130 is a suppressor of wing pouch | larval stage phenotype of Scer\GAL4^NP5130, Smox^RNAi.UAS.cPa

(Upadhyay et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

44400

w^*; P{UAS-babo.a.RNAi}attP16

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

babo^RNAi.a.UAS

babo^{miRNA.a.Scer\UAS}

babo^miRNA.a.UAS

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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